Even on the conditioned level, it’s possible to make irrevocable changes. This is why training the mind is so worthwhile.

"We hear over and over again that, because of the principle of impermanence, even Awakening must be impermanent, but that’s not true. The Buddha didn’t say that everything is impermanent, only that conditioned things are impermanent. And even on the conditioned level, it’s possible to make irrevocable changes. This is why training the mind is so worthwhile."

~ Thanissaro Bhikkhu "The Knife of Discernment" (Meditations2)

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